Nosocomial (hospital acquired) infections or HCAI* are a major cause of patient morbidity and mortality.1 Data from the US showed that nosocomial infections (NI) caused by multidrug-resistant organisms are commonly associated with up to 18 days longer hospital stays and annual estimated costs of between $5.7 and $6.8 billion.2

Reusable leads, e.g. ECG leads, have come under scrutiny as reservoirs for multidrug-resistant bacterial pathogens that may play an important role in serious NI in hospitalised patients.3

Key findings from a study, reported in Cardiology News, showed that after re-processing and immediately before planned use on other patients, 77% of the ECG cables were contaminated with one or more antibiotic-resistant nosocomial pathogens.3


Integral Process - Cables & Leadwires

The efficient & self-sufficient solution that can minimise nosocomial infections



Life-long antibacterial coating on the cables greatly impairs the survival of multi-drug resistant hospital acquired bacterial pathogens1. To help reduce patient morbidity, morality and save hospital costs2, supporting the delivery of a high quality service.


Providing high quality cables & leadwires, continuously developed and improved over more than 30 years of experience in the field. A trusted partner supplying high quality, cost effective solutions, supporting the reliable delivery of your service


We offer an extensive and fully compatible range, with the additional ability to quickly turn around new products upon requests. As a manufacturer we can meet your needs and simplify procurement, supporting the efficiency of your service


The IP Cables & Leadwires consist of a metalloacid material, molybdenum trioxide (MoO3), which has been demonstrated to have an antimicrobial effect.1,4

Mode of Action
The material surface of MoO3 reacts with H2O, forming an acidic surface. The acidic surface acts as an effective, nonspecific antimicrobial as the low pH deteriorates cell growth and proliferation.1,4

Why Use Molybdenum Trioxide for Our Cables?
There are several advantages of MoO3 coating compared to other antimicrobial solutions such as anti-adhesive, disinfectant or inorganic antimicrobial (e.g. silver or copper ions) surface coatings1

  1. IP Bio-Active Cables has a life-long antibacterial coating – A Durable Solution MoO3 is highly insoluble and stable5, resulting in a durable antimicrobial coating.
  2. IP Bio-Active Cables are not affected by emerging resistance of bacteria – An Effective Solution The MoO3 material is insensitive towards emerging resistance of bacteria.4
  3. IP Bio-Active Cables are non-cytotoxi4 – A Non-harmful Solution Clinical tests show the non-cytotoxicity of MoO3.4

Effectiveness of the Antimicrobial Properties of MoO3
Assays have been undertaken to test the effectiveness of killing microorganisms. One study confirmed the highly efficient antimicrobial activity of MoO3 towards severe infectious agents (S. aureus and P. aeruginosa), where cable surfaces were virtually free of bacteria within 6 hours after incubation with an infectious solution.4

Another study looking at nine bacterial strains and two fungi showed no difference vs control for the sporeforming microorganisms. However, the bacterial counts, after 2 to 24 hours of contact with the coated surface, were significantly lower (p<0.001) than those observed with non-coated surface.1

The Benefits of Bio Active Cables

The hospital environment poses a high risk of spreading microorganisms. The Bio Active properties of IP Cables and Leadwires can, in addition to hospital specific cleaning procedures, help to reduce hospital acquired infections, and may provide a permanent means of minimising microbial contamination between cleaning procedures.


IP Cables & Leadwires are individually packed in 100% Polyethylene, fully recyclable and environmentally friendly pouches. Nissha Medical Technologies | Healthcare Solutions strives to utilise environmentally friendly packaging, whenever possible, to ensure:

  • Packaging can be widely recycled
  • Fewer natural resources are used in production
  • Fewer waste products are generated in production & disposal
  • It is biodegradable (breaks down to carbon and hydrogen)
  • It does not generate toxic gases if burned

Bio Active Cable Compatibility Listing

  • Acuson
  • Arrow
  • Artema/SW
  • Bard
  • Bexen
  • Biolight
  • Bionet
  • Bosch
  • Cardiac Science
  • Cardiette
  • Cardioline
  • Cas Medical
  • Colin (IP)
  • Colson
  • Corometrics (GE)
  • Corpuls
  • Critikon (GE)
  • CSI Criticare
  • Datascope
  • Datex Medical
  • Diasonics Sonotron
  • Divers
  • Drager
  • Drager Siemens
  • Edan
  • Esaote Biomedica
  • Fukuda
  • GE Corometrics
  • GE Critikon
  • GE Datex-Ohmeda
  • General Electric
  • GE Honeywell
  • GE Marquette / Hellige
  • Getemed
  • Hewlett Packard
  • HME
  • Honeywell (GE)
  • Invivo-MDE
  • Ivy
  • Kontron
  • Larsen Toubro
  • Lohmeier
  • Mediana
  • Medtronic / Physio Control
  • Mennen
  • Mindray
  • Mortara
  • Nellcor (Tyco)
  • Nihon Kohden
  • Philips ATL
  • Philips Agilent Technologies
  • Protocol (Welch Allyn)
  • Respironics
  • RGB Medical Devices
  • Schiller
  • Siemens
  • Sorin
  • Spacelabs
  • St. Jude Medical
  • Toshiba
  • Tyco Nellcor
  • Welch Allyn
  • Zoll


1. Tétault N et al., ‘Biocidal activity of metalloacid-coated surfaces against multidrug-resistant microorganisms’, Antimicrob Resist Infect Control 2012, 1:35 [Accessed on 3 January 2019].
2. Reshamwala A et al., ‘Microbial Colonization of Electrocardiographic Telemetry Systems Before and After Cleaning’, Am J Crit Care, September, Vol 22(5), 2013, p. 382-9. doi: 10.4037/ajcc2013365 [Accessed on 3 January 2019].
3. Jancin B, ‘Antibiotic-Resistant Pathogens Found on 77% of ECG Lead Wires’, Cardiol News, March, Vol 2(3), 2004.
4. Zollfrank C et al., ‘Antimicrobial activity of transition metal acid MoO3 prevents microbial growth on material surfaces’, Mat Sci Engin, 32, 2011, p. 47–54.
5. AMERICAN ELEMENTS, Molybdenum Oxide [online] 2019 [Accessed on 12 January 2019].

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